This is a list of nice clients for Twitter, try & find your best mate
Everything in your sight, great interface, my favorite one
Buzzbird is a full featured, multi-platform, multi-account desktop Twitter client that does *not* require any third-party support applications (like Adobe AIR or JavaFX).
Bluebird supports some innovative concepts like XHTML/CSS Skinning. It includes a comprehensive set of features that includes Public Timeline View, Direct Messages, Multi Account Support, Skins/Themes, etc
TwitterPod is a Twitter client with message store capability. The messages by your friends and by yourself will all be stored and displayed on an easy-to-navigate window.
If you like Twitter but value a real OS X look and feel then give Nambu a try.
it’s fast, simple & awesome
Snitter is made on the Adobe AIR platform which is both Mac OSX and Microsoft Windows compatible. There is currently a Linux version of Adobe AIR in alpha testing but some functionality is likely missing.
NatsuLion is an open-source Twitter client for Mac OS X.
twhirl is a social software desktop client, based on the Adobe AIR platform.
Tweetr for mac has all the functionality you would expect of a Twitter client. The ability to view Public Tweets, @Mentions, and Direct Messages. Tweetr also has the ability to take a picture using your Mac’s iSight Camera. The Feature that places thi application above the rest is built in Tw3t Functionality. Using Tw3t means you are able to drag and drop any files and receive a link to tweet. Tw3t allows you to send Pictures, Videos, and other files to twitter users, This is also a direct download.
Spaz is a free, award-winning Twitter client for the Adobe® AIR™ platform, offering notable features such as access to direct messages and replies, CSS theming, and event sounds. Spaz is open-source under the “New BSD” license.
Canary’s main features are multiple timelines, filters to help you focus on the stuff you read, drag-and-drop TwitPic integration and an easy way to add/remove/block fellow twitterers.
A new Mac OS X Twitter app on the block, Lounge, is a multiple account Twitter app that allows you to do most things with ease, tweeting, replying, direct messages, favourites, retweet and even lets you learn more about a particular user by displaying a user’s profile, followers/following right in the app itself (very useful).
a location aware twitter client for Mac OS, Windows, Mobile.
Seesmic, the best Twitter client for Desktop, Web and Mobile, manage multiple Twitter accounts, Facebook feeds and pages and access Twitter Lists
Twitterrific is a fun application that lets you both read and publish posts or “tweets” to the Twitter community website. The application’s user interface is clean, concise and designed to take up a minimum of real estate on your Mac’s desktop.
Twucket is a new Twitter client for Mac OS X Leopard. It’s designed to use a minimal amount of screen real estate, so you can keep an eye on your Twitter feed in a window small enough to leave open all the time.
19. Twidget (Dashboard)
20. YoruFukurou (NightOwl)
is a Twitter client for Mac that allows users to save tabbed searches, customise the app’s toolbar, and has easy access buttons for sharing what you are currently listening to in iTunes or browsing in Safari.
YoruFukurou’s strength lies in how customisable the application is. You can change the colour of the text and backgrounds, using specific colours to highlight mentions or DMs in your personal timeline.
Echofon for Mac – The minimal yet powerful Twitter app that syncs unread Tweets with your iPhone.